Air distance from Madrid, Spain to Skopje, Macedonia is 1286.5 Miles (2070.4 Kilometers / 1117.2 Nautical Miles).
2 hrs, 40 mins is the flight duration between Madrid and Skopje. This is the In-The-Air flight time. You should also add the taxi time, airport wait times and possible delays due to bad weather, etc. for the total flight duration time.