Air distance from Chicago, USA to Medellin, Colombia is 2554 Miles (4110.2 Kilometers / 2217.9 Nautical Miles).
5 hrs, 18 mins is the flight duration between Chicago and Medellin. This is the In-The-Air flight time. You should also add the taxi time, airport wait times and possible delays due to bad weather, etc. for the total flight duration time.