Air distance from San Diego, USA to St. Louis, USA is 1567.6 Miles (2522.8 Kilometers / 1361.3 Nautical Miles).
Flight duration time from San Diego to St. Louis is 3 hrs, 15 mins. This is the In-The-Air flight time. You should also add the taxi time, airport wait times and possible delays due to bad weather, etc. for the total flight duration time.