Air distance from Esfahan, Iran to Sao Tome, Sao Tome And Principe is 3673 Miles (5911.1 Kilometers / 3189.6 Nautical Miles).
Flight duration time from Esfahan to Sao Tome is 7 hrs, 37 mins. This is the In-The-Air flight time. You should also add the taxi time, airport wait times and possible delays due to bad weather, etc. for the total flight duration time.